(PrabotulinumtoxinA) Jeuveau® is the newest neuromodulator on the market and is produced by Evolus. It was approved for use in 2019 and was marketed as #NEWTOX. Jeuveau® contains similar protective proteins like BOTOX® does, so some people may develop a resistance to it over time which will lessen the effects. Therefore it is recommended to alternate between using different products.